Galvanized

August 16, 2017

Our world can be corrosive – an environment able to swiftly convert the “shiny and new,” into the “dulled and the rusted.” Why so? In our physical world both beauty and blight are made possible by oxygen. A relatively rare element in the universe generally but the transformative ingredient of what makes complex (eukaryotic) life possible. It is said that, “if carbon is the foundation of life then oxygen is its fuel.”

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What’s It Worth?

July 31, 2017

An age-old question that is generally answered by – “what is someone willing to pay for it?”   As we often see, this can become quickly irrational particularly when the price is set on the hope or expectation of a future value or outcome.

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Hard to Fathom

June 14, 2017

In the mere moments required to utter and comprehend a “we are so sorry to have to tell you” diagnosis, we are transformed from an individual, a customer, a voter, a parent, son or daughter into a patient.

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The stage was set, the seats were filled, and the evening candles lighting the Royal Society’s demonstration theatre were one by one extinguished. As all eyes adjusted to the blackness of the 1705 evening, Francis Hauksbee began to slowly crank the wheel of his contraption, which in turn began to spin a carefully suspended evacuated glass globe.

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Belonging

January 16, 2017

With the 35th J.P. Morgan just behind us we enter into the bold new world of 2017 with high expectations and some instructive soul searching in-hand. As expected, innovators from across the world yet again provided the “shock and awe” of how diverse discoveries can be translated into new healthcare solutions. New ways to detect, intercept, treat and track life threatening diseases. These combined with new ways to put patients or perhaps any of us prior to being “a patient” into the center of our treatment decision.

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JPM at 10

January 6, 2017

By 1991 the biotechnology industry, as measured by our annual January gatherings in San Francisco, had just hit 10. In just over a decade, a new industry built on the ability to “cut and paste DNA” had erased the need to await the Mendelian generational clock to rewrite the blueprints of life. In just a short 10 years, remarkable investments, talents and ambitions had been mobilized and new medical and agricultural advances were emerging. Continue Reading…

Thrilling Three 2016

December 22, 2016

2016 will be recorded as the year of the “surprise” – a year that illustrated more than any in recent memory our inability to predict the outcome of near-term events, a real failure to move beyond “big data” into clear and precise “insights.” To not just “know the numbers” but to truly understand what data trends and population sentiments are “actually telling us.”

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Prove It

December 6, 2016

Proof is an elusive thing. As we witness exponential increases in information exposure, our ability to decipher fact from fiction has become exponentially more difficult as well.

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“Turn Offs”

October 13, 2016

What is sleep and why is it needed? In medical textbooks, sleep is generally defined as “a reversible behavioral state of perceptual disengagement from, and unresponsiveness to, the environment.” A state entered into by all animals, all the way down to lizards (and perhaps beyond). But why? Although much has been associated with the consequences of sleep (good and bad) the jury is still out on the biological nature of its requirement. But its evolutionary persistence – coupled with even the lethality of extreme deprivation – help to underscore its importance.

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Open

August 8, 2016

“Home is where our heart is” or so we say. Where we live, where we are from – who is part of our group and who is not – has deep and durable evolutionary and psychological roots. Along with food and clothing, shelter completes the base of Maslow’s hierarchal pyramid of human needs.

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